Diuretika ovlivňují množství vylučované moči a přímo působí na ledviny. Blokují zpětnou resorpci vody v tubulech a tím způsobují ztráty tekutin v hodnotách až několika litrů denně. V lékařství se používají k léčení vysokého krevního tlaku a při nadměrném zadržování tekutin v těle.
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Biochemické procesy v organismu rozdělujeme na katabolické a anabolické. Při dějích anabolických probíhá výstavba nových tkání, při katabolických naopak. Anabolické procesy způsobují anabolické látky a právě ty jsou v současné době v dopingu závažným problémem. Můžeme je rozdělit na anabolické androgenní steroidy a na ostatní anabolické látky.
Proč jsou zneužívány androgenní steroidy? Již dříve si lidé všimli, že varlata zodpovídají za rozvoj sekundárních
Používají se pro povzbuzení, pro potlačení únavy, zvýšení soutěživosti a agresivity. Mezi nejběžnější patří kofein, kokain, amfetamin, efedrin a pseudoefedrin.
AMFETAMINY: Mají podobný účinek i strukturu jako tělu vlastní hormon adrenalin. Ten je v těle vylučován v případě ohrožení a zvyšuje krevní tlak, srdeční frekvenci a připravuje tělo na útěk či boj. Tyto látky byly zneužívány k dopingu jako jedny z prvních. Jsou zaznamenány četná úmrtí,
Otevírám na Lezci nové téma a byl bych rád, kdyby se k němu lépe informovaní vyjádřili, zejména trenéři a závodníci. Lezení na špičkové úrovni je sport jako každý jiný. V honbě za úspěchem jsou někteří sportovci ochotni použít zakázané prostředky. Co je tedy doping?
1. užití prostředku (látky nebo metody), který je potencionálně škodlivý zdraví sportovců nebo je schopný zvýšit jejich výkon, nebo obojí.
2. Přítomnost zakázané látky v těle sportovce nebo důkaz o jejím užití nebo důka
Druhý zářijový víkend se v Insbrucku vyznačoval zvýšenou hustotou výskytu horolezeckých osobností světa. Důvod byl prostý. Vůdčí osobnosti horolezeckého sportu uplynulého století, současná lezecká špička horského lezení a zástupci horolezeckých organizací diskutovali v rámci kongresu o budoucnosti horolezeckého sportu v horách v několika tématech. Výsledkem kongresu je \\\"Tyrolská deklarace\\\", určitý souhrn, kodex k provozování současného alpinismu.
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Diuretika ovlivňují množství vylučované moči a přímo působí na ledviny. Blokují zpětnou resorpci vody v tubulech a tím způsobují ztráty tekutin v hodnotách až několika litrů denně. V lékařství se používají k léčení vysokého krevního tlaku a při nadměrném zadržování tekutin v těle.
Ve sportu se diuretika používají ve sportech s váhovými kategoriemi, box, judo, zápas, vzpírání, a ve sportech, kde je výhodná nižší tělesná hmotnost. Kromě jezdectví to může být i lezení. Diuretika také dokáží maskovat používání jiných zakázaných látek, protože snižují možnost jejich laboratorního zjištění.
PEPTIDOVÉ HORMONY A JIM PODOBNÉ LÁTKY
Tyto látky jsou tělu vlastní a zjištění jejich zneužití bylo do nedávné doby nesnadné.
1. EPO
Nejznámější látkou je EPO – erytropoetin. Donedávna masově používaný ve vytrvalostních sportech. Aféry z Tour de France 1998 či na MS v klasickém lyžování v Lahti 2001 toto tvrzení potvrzují a jedná se jen o špičku ledovce. EPO je zakázáno od roku 1990 a užívá se pouze injekčně. EPO stimuluje tvorbu červených krvinek v kostní dřeni a udržuje jejich optimální množství v krvi. Jediné legální metody, jak zvýšit množství červených krvinek jsou pobyty ve vysokohorském prostředí a hypobarické místnosti, oproti užívání EPO metody poněkud složité a drahé. Průměrné zastoupení červených krvinek v objemu krve je 38 až 48 % u mužů, o 2 – 3 % méně u žen, vyjadřuje se v tzv. SI jednotkách 0,38 – 0,48. Při podání EPO se tyto hodnoty zvyšují na 0,50 až 0,56. Při těchto hodnotách se zvyšuje viskozita krve a může dojít k poškození kardiovaskulárního systému. Do nedávné doby se zvýšení nad 0,50 považovalo za nepřímý důkaz užití EPO a dotyčnému nebyl povolen start z důvodu ohrožení zdraví. Další krevní test se prováděl za 14 dní a byl-li krevní obraz v pořádku, byla povolena další činnost. Po olympiádě v Sydney 2000 se vyvinuly dvě laboratorní metody na zjištění vnějšího podání EPO. Že se jimi dokáží najít i EPO podobné látky jako například darbopoetin, ukázala letošní zimní olympiáda v Salt Lake City. Komm, Johann, Komm! EPO by se dalo použít ve výškovém horolezectví v rámci urychlení aklimatizace. Nebylo by špatný v Praze zmnožit krvinky, na pohodu vystoupit v Lukle z letadla a jakoby nic vystoupat do 6000 m. Zatím mi to připadá dost úchylný nápad, ale kdo ví?
2. STH
Somatotropní neboli růstový hormon je vylučován podvěskem mozkovým a podporuje růst všech orgánů a rozkládání tuku v těle. Dříve se získával z podvěsku mozkového zemřelých lidí a opic. Záhy se zjistilo, že hrozí nákaza Creutzfeld – Jakobovou nemocí, a počátkem 80.let se STH začal vyrábět synteticky pomocí bakterií. Ve sportu se používá po vysazení steroidů před soutěží, aby se předešlo ztrátě svalové hmoty.
3. Inzulín
Hormon, který je velmi důležitý v metabolismu cukrů. Bývá zneužíván pro anabolické účinky v sacharidové i proteinové oblasti. Podle odborníků je jeho užívání hra s ohněm, která se nemusí vyplatit a neodrazují od ní ani těžké problémy diabetiků. Inzulín mohou ve sportu užívat jen diabetici, ale musí o tom informovat příslušný antidopingový orgán.
ZAKÁZANÉ DOPINGOVÉ METODY
Z metod jen stručně o krevním dopingu.
Krevní doping
Jedná se o infuzi krve nebo krevních derivátů přímo do žíly sportovce. Obvyklý postup je takový, že několik měsíců před soutěží je sportovci odebrána krev, červené krvinky se oddělí od plasmy a uskladní se. Tyto krvinky se krátce před soutěží vpraví do sportovcova krevního řečiště a to zvýší transportní kapacitu jeho krve pro kyslík. Je možno podat i krev okysličenou. Nemusí se přitom jednat o krev toho samého sportovce. Tato metoda je riziková kvůli možnému přenosu AIDS a jiných infekčních chorob a v době EPO je prý na ústupu, což v době zlepšení testů na EPO nemusí platit.
Tímto končí miniseriál o dopingu. Zatím se v komentářích neozval nikdo ze závodníků či výškových horolezců se svým názorem nebo zkušenostmi, škoda. Moji výzvu s tím zákonem o cenzuře neberte vážně. Byla to rychlá reakce na obavy Hopa jako provozovatele těchto stránek, už je nemá. Tak někdy příště s lezečtějším tématem.
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